Quantification of Cell Adhesivity with the OWLS Biosensor System

Abstract
The molecular interactions and cell-biological mechanisms behind the adhesive behavior of a cell are not properly understood. In the last decades, the development of bio-protheses and the hope for elaboration of successful cell replacement therapies accelerated the search for appropriate scaffold materials and conditions which may help to keep cells alive and functioning on artificial surfaces. For understanding some crucial steps of cell-attachment, the initial phases of attachment of two different types of cloned cells – NE-4C neural stem and MDCK epithelial cells - were analyzed by optical waveguide light mode spectroscopic (OWLS) methods, See the application note embedded below:


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